Spectrum Pharma’s blood cancer drug meets trial goal






(Reuters) – Spectrum Pharmaceuticals Inc said a mid-stage trial of its experimental blood cancer drug met the main goal of reducing the size of tumors.


The biotechnology company‘s shares, which have fallen about 22 percent over the past 12 months, were up about 3 percent at $ 11.60 in morning trade on the Nasdaq and touched a high of $ 11.75 .






The drug, belinostat, was tested in patients with relapsed or refractory peripheral T-Cell lymphoma (PTCL), and who had failed to respond to at least one therapy.


The company said it expects to file a marketing application with U.S. health regulators by mid-2013, and expects a review date in 2014.


The trial was conducted under a special protocol assessment that provides a company with a written agreement that the design of the study and analysis of the data are adequate to support a marketing application with the U.S. health regulator.


Spectrum markets another drug to treat PTCL, named Folotyn, which it obtained as part of its acquisition of cancer drugmaker Allos Therapeutics earlier this year.


MLV & Co analyst George Zavoico said Folotyn and belinostat have different mechanisms of action, and having two drugs for the same indication could be useful in cases of relapsed patients who develop resistance to one of them.


PTCL consists of a group of aggressive blood cancers that develop from T-cells, a class of white blood cells.


(Reporting By Vrinda Manocha in Bangalore; Editing by Don Sebastian and Sreejiraj Eluvangal)


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The Year’s Best & Worst Investments






Winners
Best International Stock (+283%): India consumes more than $ 20 billion worth of whiskey each year—the most in the world—and United Spirits (UNSP) is the nation’s largest distiller. The company’s sales doubled in four years. The United Kingdom’s Diageo (DEO) bought a controlling stake in United Spirits in November.
 
1f6ae  inv bestworst2 202 The Years Best & Worst InvestmentsBest U.S. Large-Cap Stock (+224%): The good news for Regeneron Pharmaceuticals (REGN) shareholders included strong sales for a treatment for eye diseases. Total revenue jumped fourfold last quarter. The Tarrytown (N.Y.)-based company also won approval for a chemotherapy drug and is developing treatments for rheumatoid arthritis and high cholesterol.
 
Best Bond Fund (+26%): The GMO Emerging Country Debt Fund (GMCDX) invests in debt issued by emerging-market countries, a strategy that’s worked in nine of the last 10 years. Its top holding is Venezuelan bonds, a sign that its managers are willing to take risks in particularly unstable countries.
 
1f6ae  inv bestworst3 202 The Years Best & Worst InvestmentsBest Initial Public Offering (+105%): Retailer Five Below (FIVE) sells candy, stationery, and beauty products priced at $ 5 or less and aimed at teenagers. Sales are growing 47 percent a year.
 
Best Equity Mutual Fund (+39%): The Fidelity Select Biotechnology Portfolio (FBIOX) spreads $ 2.7 billion in assets over 131 biotechnology stocks. A top holding: Gilead Sciences (GILD), the California-based biopharmaceutical company.
 
1f6ae  inv bestworst4 2021 The Years Best & Worst InvestmentsBest Commodity (+24%): Wheat prices rose in 2012 as drought cut into supply from the grain belts of Russia, Australia, and the U.S. Wheat is a $ 14.4 billion crop in the U.S., where it ranks fourth behind corn, soybeans, and hay.
 
Best Exchange-Traded Fund (+77%): Signs of a housing recovery sent shares of homebuilders soaring this year, boosting the IShares Dow Jones U.S. Home Construction Index Fund (ITB).
 
Losers
Worst Exchange-Traded Fund (-79%): The ProShares VIX Short-Term Futures ETF (VIXY) holds futures contracts that are profitable when the VIX index, a measure of U.S. stock market volatility, rises. 2012 was a calm year.
 
1f6ae  inv bestworst7 202 The Years Best & Worst InvestmentsWorst Commodity (-35%): Abundant supply is depressing coffee prices. Brazil, the world’s largest grower, has almost doubled its output in the past decade, producing another record crop this year.
 
Worst Equity Mutual Fund (-17%): The Federated Prudent Bear Fund (BEARX) holds gold mining stocks and other investments it expects will do well in times of financial stress. That strategy suffers in years such as 2012, when stocks rise.
 
1f6ae  inv bestworst8 202 The Years Best & Worst InvestmentsWorst Initial Public Offering (-30%): Facebook (FB) plunged as much as 53 percent after its $ 16 billion debut in May. The stock rallied on news that third-quarter sales rose 32 percent, beating analysts’ estimates.
 
Worst Bond Fund (+.12%): While the GMO U.S. Treasury Fund (GUSTX) may just barely be holding its value at yearend, its extremely cautious strategy means returns aren’t keeping up with inflation. The fund is invested entirely in U.S. Treasury bills, government debt that matures in less than a year.
 
1f6ae  inv bestworst10 202 The Years Best & Worst InvestmentsWorst U.S. Large-Cap Stock (-43%): Hewlett-Packard’s (HPQ)annus horribilis was marked by a third-quarter loss that was its worst ever, including an $ 8 billion writedown related to the dwindling value of its enterprise services business. HP later took an $ 8.8 billion writedown related to accounting problems at Autonomy, a software maker it acquired last year. In September, HP announced plans for 29,000 job cuts.
 
Worst International Stock (-81%): The biggest target for the European Union’s bailout fund for Spanish banks, Bankia (BKIA), forecasts it will lose $ 25 billion in 2012. The bank, formed last year from the merger of seven regional savings banks damaged by Spain’s real estate downturn, is in the midst of cutting more than a quarter of its workforce.


Data compiled by Bloomberg from Dec. 31, 2011, to Dec. 17, 2012. Criteria – Bond Funds: 725 bond mutual funds based in the U.S. with assets of $ 500 million or more. Commodities: 18 global commodities tracked by Bloomberg. Equity Mutual Funds: 796 U.S.-based equity mutual funds with assets of $ 1 billion or more. Exchange-Traded Funds: 1,062 U.S.-based ETFs, excluding those that use leverage. Initial Public Offerings: 103 U.S. IPOs with an offer size of at least $ 100 million. International Stocks: The MSCI AC World Index. Large-Cap Stocks: 367 stocks on U.S. exchanges with market value of more than $ 10 billion.






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Italy PM Monti resigns, elections likely in February






ROME (Reuters) – Italian Prime Minister Mario Monti tendered his resignation to the president on Friday after 13 months in office, opening the way to a highly uncertain national election in February.


The former European commissioner, appointed to lead an unelected government to save Italy from financial crisis a year ago, has kept his own political plans a closely guarded secret but he has faced growing pressure to seek a second term.






President Giorgio Napolitano is expected to dissolve parliament in the next few days and has already indicated that the most likely date for the election is February 24.


In an unexpected move, Napolitano said he would hold consultations with political leaders from all the main parties on Saturday to discuss the next steps. In the meantime Monti will continue in a caretaker capacity.


European leaders including German Chancellor Angela Merkel and European Commission President Jose Manuel Barroso have called for Monti’s economic reform agenda to continue but Italy’s two main parties have said he should stay out of the race.


Monti, who handed in his resignation during a brief meeting at the presidential palace shortly after parliament approved his government’s 2013 budget, will hold a news conference on Sunday at which he is expected clarify his intentions.


Ordinary Italians are weary of repeated tax hikes and spending cuts and opinion polls offer little evidence that they are ready to give Monti a second term. A survey this week showed 61 percent saying he should not stand.


Whether he runs or not, his legacy will loom over an election which will be fought out over the painful measures he has introduced to try to rein in Italy’s huge public debt and revive its stagnant economy.


His resignation came a couple of months before the end of his term, after his technocrat government lost the support of Silvio Berlusconi‘s centre-right People of Freedom (PDL) party in parliament earlier this month.


Speculation is swirling over Monti’s next moves. These could include outlining policy recommendations, endorsing a centrist alliance committed to his reform agenda or even standing as a candidate in the election himself.


The centre-left Democratic Party (PD) has held a strong lead in the polls for months but a centrist alliance led by Monti could gain enough support in the Senate to force the PD to seek a coalition deal which could help shape the economic agenda.


BERLUSCONI IN WINGS


Senior figures from the alliance, including both the UDC party, which is close to the Roman Catholic Church, and a new group founded by Ferrari sports car chairman Luca di Montezemolo, have been hoping to gain Monti’s backing.


He has not said clearly whether he intends to run, but he has dropped heavy hints he will continue to push a reform agenda that has the backing of both Italy’s business community and its European partners.


The PD has promised to stick to the deficit reduction targets Monti has agreed with the European Union and says it will maintain the broad course he has set while putting more emphasis on reviving growth.


Berlusconi’s return to the political arena has added to the already considerable uncertainty about the centre-right’s intentions and increased the likelihood of a messy and potentially bitter election campaign.


The billionaire media tycoon has fluctuated between attacking the government’s “Germano-centric” austerity policies and promising to stand aside if Monti agrees to lead the centre right, but now appears to have settled on an anti-Monti line.


He has pledged to cut taxes and scrap a hated housing tax which Monti imposed. He has also sounded a stridently anti-German line which has at times echoed the tone of the populist 5-Star Movement headed by maverick comic Beppe Grillo.


The PD and the PDL, both of which supported Monti’s technocrat government in parliament, have made it clear they would not be happy if he ran against them and there have been foretastes of the kind of attacks he can expect.


Former centre-left prime minister Massimo D’Alema said in an interview last week that it would be “morally questionable” for Monti to run against the PD, which backed all of his reforms and which has pledged to maintain his pledges to European partners.


Berlusconi who has mounted an intensive media campaign in the past few days, echoed that criticism this week, saying Monti risked losing the credibility he has won over the past year and becoming a “little political figure”.


(Additional reporting by Gavin Jones, Massimiliano Di Giorgio and Paolo Biondi; Writing by Gavin Jones and James Mackenzie; Editing by Michael Roddy)


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Reacting to users’ outcry, Facebook’s Instagram reverts to prior policy on advertising






SAN FRANCISCO – Instagram has abandoned wording in its new terms-of-service agreement that sparked outcry from users concerned it meant their photos could appear in advertisements.


In a blog post late Thursday, the popular mobile photo-sharing service says it has reverted to language in the advertising section of its terms of service that appeared when it was launched in October 2010.






Instagram is now owned by Facebook Inc. and maintains that it would like to experiment with different forms of advertising to make money.


Its blog post says that it will now ask users’ permission to introduce possible ad products only after they are fully developed.


The outcry to the changes announced earlier this week led the company to clarify that it has no plans to put users’ photos in ads.


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Mission Impossible?: Can Tom Cruise Launch a Box-Office Franchise with ‘Jack Reacher’?






LOS ANGELES (TheWrap.com) – Paramount hopes it’s launching a franchise with “Jack Reacher,” the Tom Cruise action thriller that hits theaters Friday.


It will be tricky in a crowded holiday marketplace, and Cruise isn’t the box-office bonanza he once was. But one need only look back to last year’s “Mission: Impossible – Ghost Protocol” to see how it might work. That film opened to $ 12 million on December 16 and went on to make $ 209 million and nearly $ 700 million worldwide for Paramount.






Jack Reacher” will be in about 3,200 theaters, and it will have plenty of competition. Universal’s Judd Apatow comedy “This Is 40″ opens wide Friday, and Paramount‘s ‘Guilt Trip” and Disney’s 3D re-release of “Monsters Inc.” opened Wednesday.


A slew of limited releases, led by Kathryn Bigelow’s “Zero Dark Thirty,” along with this year’s winner of the Palme d’Or at Cannes “Amour,” and tsunami survival tale “The Impossible” are also competing for moviegoers’ attention, along with a number of holdover hits.


No movie, though, will come close to catching reigning box-office champ “The Hobbit: An Unexpected Journey,” which remains in more than 4,000 theaters. Peter Jackson’s latest Middle-earth epic will take in north of $ 40 million, industry analysts say, with “Jack Reacher” and “This Is 40″ battling for second with less than half of that.


Warner Bros.’ “Hobbit” has rolled to $ 106 million in the U.S. since opening to $ 85 million last weekend. Its international total – $ 188 million as of Thursday – is even bigger.


In “Jack Reacher,” Cruise plays an ex-military investigator; the film is based on bestselling author Lee Child’s novel “One Shot” and written for the screen and directed by Christopher McQuarrie. It’s from David Ellison’s Paramount-based Skydance Productions and was produced for about $ 60 million by Cruise, Don Granger, Paula Wagner and Gary Levinsohn.


Robert Duvall and Richard Jenkins co-star in the PG-13 crime thriller, which has a 53 percent positive rating at Movie Review Intelligence.


No is expecting “Jack Reacher” to match “MI:4″ at the box office. The Reacher novels have a following, but nowhere near that of the “Mission Impossible” franchise. Cruise’s recent box-office record has been uneven, and the film’s Facebook and Twitter activity is not particularly strong.


Jack Reacher” could wind up playing more like Cruise’s “Knight and Day,” which opened to $ 20 million and went on to make $ 76 million for Fox in 2010, or “Valkyrie,” which did $ 83 million in 2008 after opening to $ 21 million. Cruise was critically lauded for his foray earlier this year as an aging rock icon in the musical “Rock of Ages,” but that was one of the year’s bigger box-office duds.


Jack Reacher” should play strongly with action fans, but Cruise’s personal problems could limit its broader appeal.


“I can’t imagine his divorce from Katie Holmes and the custody battle hasn’t hurt him some with women,” BoxOffice.com vice president and chief analyst Phil Contrino told TheWrap Thursday. “Actions fans will come out, but going beyond that demographic is going to be tough for him.”


On the other hand, Universal says that it tracking suggests “This Is 40″ will do quite well with women — and women over 25 in particular.


“This Is 40,” is, as the marketing campaign points out, a “sort of sequel” to Apatow’s “Knocked Up,” which opened to $ 30 million and went on to make nearly $ 150 million five years ago. Like “This Is 40,” that one was written and directed by Apatow and starred Paul Rudd and Leslie Mann.


“40″ is the fourth film Apatow has directed, all for Universal (“Funny People” and “40-Year-Old Virgin” are the other two). The ensemble cast also features Albert Brooks, John Lithgow, Megan Fox, Maude Apatow, Iris Apatow, Chris O’Dowd, Jason Segel, Melissa McCarthy and Lena Dunham.


It’s R-rated and has a 62 percent positive rating at Movie Review Intelligence. The production budget was $ 35 million.


“This looks like the strongest comedy of the season,” Jeff Bock, senior analyst at Exhibitor Relations told TheWrap, “but it’s still a bit of a wild card. It’s going to connect with the New York and L.A. crowds; the key will be whether the Heartland audiences embrace it or see it as a little too hip. It will take time to tell, because of the season.”


Films released at this time of year tend to open lower because the marketplace is so crowded – by Friday, 11 new films will have hit opened this week – and the fact that many potential moviegoers are districted by shopping and other holiday preps. On the other hand, they often show lasting power and make up what they don’t take in on the weekend with stronger showings on the weekdays.


“Things could well come in lower than people are expecting across the board this weekend,” Bock said, “but look for many of these movies to make it up over the holidays.”


Summit will be looking for that kind of slow build on “The Impossible,” the English-language film from Spain based on a true story about a family’s fight to survive the 2004 tsunami in Thailand. Ewan McGregor and Naomi Watts, who received a Best Actress nomination from SAG recently, star.


Summit is releasing it Friday in 15 theaters in New York, Los Angeles, Chicago, Philadelphia, Phoenix, San Francisco, Washington, D.C., and Toronto. The plan is to go nationwide early next year.


“The Impossible” already has taken in $ 52 million in Spain, the home of the real-life couple upon whom the story is based as well as director Juan Antonio Bayona (“The Orphanage”) and screenwriter Sergio Sanchez.


Other limited rollouts set for Friday include Paramount‘s 3D concert film “Cirque du Soleil: Worlds Away,” in 800 theaters; “On the Road,” IFC Films’ adaptation of the Jack Kerouac’s beat generation novel, in four theaters; and “Not Fade Away,” the Paramount Vantage tale of a group of 1960 New Jersey friends launching a rock band, written and directed by “Sopranos” creator David Chase, in three locations.


Sony’s “Zero Dark Thirty,” about the manhunt for Osama bin Laden, got off to a terrific start Wednesday. It racked up $ 124,848 from five theaters in its first day of release. That’s an average of $ 24,969, making it one of the biggest limited mid-week openings in history.


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Women’s Excellence in Endometriosis: Introducing a Specialized Center Treating Pelvic Pain, Painful Intercourse, and Painful Menstrual Periods in Oakland County, MI






Endometriosis is a painful, sometimes disabling disease that attacks a woman’s reproductive tract and other pelvic organs and can ultimately lead to infertility and chronic pelvic pain (CPP). Women’s Excellence in Endometriosis is a one-of-a-kind, specialty center for woman suffering with the disease and its painful sequelae.


Oakland County, MI (PRWEB) December 20, 2012






Women with chronic pelvic pain (CPP) may likely have a condition called “Endometriosis.” Endometriosis is a disease affecting the female reproductive tract in which the endometrial lining of the uterus spreads into the pelvic cavity, implanting itself on the pelvic structures, causing inflammation and pain. Symptoms of endometriosis include painful menstrual periods (dysmenorrhea) which cannot be relieved with typical over-the-counter pain medications such as acetaminophen or ibuprofen, irregular periods, pelvic pain, painful sexual intercourse, and/or difficulty conceiving a pregnancy. Untreated, endometriosis can lead to chronic pelvic pain (CPP), infertility, and disability in women.


Women’s Excellence in Endometriosis is a specialty center designed to treat women with this chronic condition in a multidisciplinary fashion. Dr. Jonathan Zaidan has established himself as an expert in diagnosing and treating endometriosis. Dr. Zaidan is trained and credentialed in minimally invasive robotic surgery to treat endometriosis. Working primarily out of McLaren Oakland hospital in Pontiac, MI, Dr. Zaidan can remove most and sometimes all disease through this procedure. According to Dr. Zaidan, “Robotic resection of endometriosis is the most advanced treatment for the disease and can even provide a surgical cure for some individuals. The procedure is minimally invasive, which means no large incisions, patient goes home the same day in most cases, and recovery is much easier and faster”.


Endometriosis can only be definitively diagnosed with laparoscopy, which is a minimally invasive surgical procedure that allows the surgeon to view the pelvic cavity with a small scope and visualize the disease. “Once diagnosis has been confirmed, in most cases we start the patient on a six-month regimen of Lupron or Zoladex therapy. A monthly dose of either of these medications halts the production of estrogen and puts the patient into a temporary medical menopause, which gives the body’s natural immune system a chance clear as much of the endometriosis as possible, before going back into surgery for the robotic resection”, states Debbie Henry, NP-C, nurse practitioner at Women’s Excellence in Endometriosis. “We have found this protocol to be highly successful for most patients, especially since endometriosis appears to be an estrogen dependent disease”, adds Henry. After the robotic resection of endometriosis, hormonal suppression of estrogen is prescribed, usually in the form of a birth control option such as Depo Provera or a combined oral contraceptive pill (COCPS), in order to retard a resurgence of the disease.


“Women with endometriosis are dealing with a chronic illness and need specialized care. We just felt that we could not give these patients adequate time and the quality of care that they really needed in a busy OB/GYN setting, sandwiched between routine OB visits and annual exams”, states Zaidan. “We provide an inviting, calming atmosphere here at Women’s Excellence in Endometriosis; these patients are dealing with a stressful, chronic condition and the last thing they need is a long wait or a quick visit. We are able to provide longer patient visits at this center. Our patients really become like family to us”, Henry offered.


For women who are knowingly dealing with endometriosis or dealing with chronic symptoms that could likely be endometriosis, Women’s Excellence in Endometriosis offers a comprehensive, specialized treatment with a compassionate touch. From the reception staff, to the medical assistants, to the providers, Women’s Excellence in Endometriosis’ mission is to provide timely, evidenced-based care, in a compassionate way. “We have helped hundreds of patients are we are eager to help hundreds more”, concludes Henry.


Founded by Dr. Jonathan Zaidan, Women’s Excellence in Endometriosis is a comprehensive center for women that have either been diagnosed with endometriosis or have the symptoms of endometriosis. Women’s Excellence in Endometriosis utilizes the latest and best treatment protocols to effectively treat the symptoms and sequelae of endometriosis. Whether a woman has known endometriosis or seeking a diagnosis for symptoms of painful sexual intercourse, painful periods, chronic pelvic pain or irregular bleeding, Women’s Excellence in Endometriosis is designed to diagnose, treat and improve the symptoms of endometriosis and chronic pelvic pain (CPP). Women’s Excellence in Endometriosis treats all women with these symptoms including those women in the teenage years, women who are desiring to conceive a pregnancy, as well as women who are done childbearing. The knowledgeable, well trained, compassionate physicians and healthcare providers of Women’s Excellence in Endometriosis are now accepting new patients. Call for an appointment today (248) 693-1630 or visit http://www.centerofendometriosis.com.


Jonathan Zaidan, MD
Women’s Excellence in Endometriosis
248 693 1630
Email Information


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Europe Needs Less Financial Integration, Not More






“More Europe” is always the solution when leaders like German Chancellor Angela Merkel talk about Europe’s slow-burning financial crisis. To qualify for emergency aid, they say, countries like Greece and Spain must surrender control of their banks and budgets to supra-national authorities. Another brick of the “more Europe” edifice was cemented into place on Dec. 13 when finance ministers of the 17-nation euro zone agreed to unified banking supervision under the European Central Bank. That’s a step toward a banking union, which is a step toward fiscal union, which is a step toward, someday, political union.


But it’s hard to see the way to a United States of Europe when every move in that direction has Europeans at each other’s throats. Thousands of protesters took to the streets in Madrid and Barcelona on Dec. 17 in the latest demonstrations against austerity. Germans, meanwhile, complain that they’re being played for suckers by Spain and Greece. In a November poll, 46 percent of Germans favored letting Greece go bankrupt.






If ordinary Europeans balk at forming one happy family, must Europe disintegrate? Or is there a middle ground that would retain many of the advantages of unity while dodging the parts that make everybody mad? The coming year may answer the question of whether Euro Lite is a way out for the union or another false hope.


Some analysts argue that stopping short of full financial integration could make Europe more stable, not less. Avinash Persaud, chairman of Intelligence Capital Limited, a London-based financial adviser, says the real problem regulators need to address is controlling the booms rather than cleaning up after the busts. National regulators, he argues, might do a better job than a single, Europe-wide regulator of stopping excessive lending in one part of Europe. They weren’t vigilant enough in the last bubble, but Persaud is concerned that the European Central Bank will do worse. Its job is to promote commonality, making it “inherently averse” to enforcing tougher lending criteria in boom countries, he says. “Banks would pounce on rules limiting their lending in booming countries, accusing the regulator of fragmenting the single market,” Persaud said in an e-mail message. “The reins holding back the booms, already too loose, have just been loosened further” by the creation of a single banking supervisor, Persaud writes in an as-yet-unpublished article. “The euro,” Persaud says, “needs to be saved from the Europhiles.”


Another “less Europe” proposal would introduce national currencies alongside the euro. Mazen Skaf, a partner and managing director in the consulting firm Strategic Decisions Group, argues in a new white paper that nations such as Greece and Spain should have the option to issue new currencies for domestic transactions, including payment of salaries and benefits. Through a controlled depreciation, the nation’s labor and pension costs would fall. External debts would still be in euros. The plan would give countries “maneuvering space to drive monetary and fiscal policy on a local basis,” Skaf argues.


None of this is easy. Barry Eichengreen, an economist at the University of California at Berkeley who studies financial crises, says investors would regard the partial reintroduction of national currencies as a prelude to leaving the euro entirely—and yank their money out. He’s also skeptical of Persaud’s national-level regulation. He says a single bank supervisor would do a better job of spotting cross-border problems, such as the inflating of Spain’s and Greece’s bubbles by loans from German banks.


af97d  econ europe52  01inline  405 Europe Needs Less Financial Integration, Not More


Finding the right balance between national sovereignty and a tighter union for Europe is the trick. Take banking regulation. Once the euro was introduced, a banking union with a lender of last resort became the logical next step: National central banks can’t bail out their economies once they don’t have their own currencies to lend. But Merkel and the Germans won’t go along with a bank bailout mechanism financed by euro-zone governments unless there’s fiscal union—i.e., shared budgets. Right now Europe is very far from sharing a budget. Spending by the European Union accounts for only 1 percent of the EU’s gross domestic product, vs. 23 percent for federal spending in the U.S. Eichengreen suggests the EU’s budget might expand to perhaps 4 percent of GDP—enough to shore up national unemployment insurance funds in times of severe recession or to fix or close banks as needed. Spending on that scale probably wouldn’t require approval by “a European Parliament that acquires all the powers of a full parliament,” he says.


Jean Pisani-Ferry, director of Bruegel, a Brussels-based think tank, sees both sides. He says Europe’s monetary union is unstable without banking and fiscal union. He also says believers in more integration “shouldn’t use any opportunity to push for … building a federal Europe. You should look at what is necessary for the euro to work.” For Europe, that balancing act isn’t going away.


The bottom line: Economists on both sides of the Atlantic are searching for a middle ground that would save the euro without going all the way to full union.


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Wounded presage health crisis for postwar Syria






ATMEH, Syria (AP) — A baby boy joined the ranks of Syria’s tens of thousands of war wounded when a missile fired by Bashar Assad‘s air force slammed into his family home and shrapnel pierced his skull.


Four-month-old Fahed Darwish suffered brain damage and, like thousands of others seriously hurt in the civil war, he will likely need care well after the fighting is over. That’s something doctors say a post-conflict Syria won’t be able to provide.






Making things worse, there has been a sharp spike in serious injuries since the summer, when the regime began bombing rebel-held areas from the air, and doctors say a majority of the wounded they now treat are civilians.


This week, Fahed was recovering from brain surgery in an intensive care unit, his head bandaged and his body under a heavy blanket, watched over by Mariam, his distraught 22-year-old mother.


She said that after her first-born is discharged from the hospital in Atmeh, a village in an area of relative safety near the Turkish border, they will have to return to their village in a war zone in central Syria.


“We have nowhere else to go,” she said.


Even for those who have escaped direct injury, the civil war is posing a mounting health threat. Half the country’s 88 public hospitals and nearly 200 clinics have been damaged or destroyed, the World Health Organization says, leaving many without access to health care. Diabetics can’t find insulin, kidney patients can’t reach dialysis centers. Towns are running out of water-purifying materials. Many of the hundreds of thousands displaced by the fighting are exposed to the cold in tents or unheated public buildings.


“You are talking about a public health crisis on a grand scale,” said Dr. Abdalmajid Katranji, a hand and wrist surgeon from Lansing, Michigan, who regularly volunteers in Syria.


No one knows just how many people have been injured since the uprising against Assad erupted in March 2011, starting out with peaceful protests that turned into an armed insurgency in response to a violent government crackdown.


More than 43,000 have been killed in the past 21 months, said Rami Abdul-Rahman, head of the Britain-based Syrian Observatory for Human Rights, basing his count on names and details provided by activists in Syria. He said the number of wounded is so large he can only give a rough estimate, of more than 150,000.


Casualties began to rise dramatically at the start of the summer. At the time, the regime, its ground troops stretched thin, began bombing from the air to prevent opposition fighters from gaining more territory.


Seemingly random bombings have razed entire villages and neighborhoods, driving terrified civilians from their homes, with an estimated 3 million Syrians out of the country’s population of 23 million now displaced.


About 10 percent of the wounded suffer serious injuries and many of those will need long-term care and rehabilitation, said Dr. Omar Aswad of the Union of Syrian Medical Relief Organizations, an umbrella for 14 aid groups.


This includes artificial limbs and follow-up surgery. “This is of course not available and will be one of the major (health) problems in the months right after the war,” said Mago Tarzian, emergency director for the Paris-based Doctors Without Borders.


For now, aid groups are struggling to provide even emergency treatment in under-equipped clinics.


The two dozen small hospitals and field clinics in rebel-run areas of Idlib province in the north only have a few Intensive Care Unit beds between them, said Aswad. None has a CT scanner, an important diagnostic tool.


“We need generators, we need medical supplies and the most pressing is medicine,” he said.


The challenge has been compounded by new types of injuries.


The regime has begun dropping incendiary bombs that can cause severe burns, according to the New York-based Human Rights Watch, citing amateur video and witness accounts.


Ole Solvang, a researcher for the group, said he saw remnants of such a bomb on a recent Syria trip. Aswad said doctors in Idlib and nearby Aleppo province reported seeing patients with burns from such weapons.


Doctors and hospitals have also been targeted. Aswad, who fled the city of Idlib in March after regime forces entered it, said five friends in a secret association of anti-regime physicians have been arrested. Hospitals, ambulances and doctors have been attacked, Solvang said, calling it “a worrying trend that makes the medical situation even worse.”


One of the bright spots is a 50-bed emergency care clinic set up six weeks ago in a former elementary school in Atmeh.


Largely funded by a wealthy Syrian expatriate, the Orient clinic, with five ICU beds, handles some of the most serious cases in a radius of some 150 kilometers (90 miles), said its director, orthopedic surgeon Abdel Hamid Dabbak.


In the past, seriously wounded patients had to go to Turkey, risking dangerous delays at the border, he said. Now, once patients are stabilized in Atmeh, they are sent to a sister clinic across the border for follow-up care.


In Orient’s ICU, a 24-year-old rebel fighter was breathing oxygen through a mask. He had been brought in a day earlier, bleeding heavily from stomach wounds and close to death, said Dr. Maen Martini, a volunteer physician from Joliet, Illinois. After surgery, he stabilized and was taken off a respirator. A delayed crossing into Turkey would have killed him, Martini said.


The fighter’s neighbor was little Fahed, whose house had been struck by a missile on Saturday in the village of Kafr Zeita in Hama province. “The roof collapsed on us,” his mother said of the attack. “We ran out … I saw him bleeding from his head, but it was just a small cut.”


The local clinic said the injury was more serious than it seemed and the family rushed to Atmeh, more than 100 kilometers (60 miles) to the north.


Since surgery, Fahed has been nursing and has moved his arms and legs, and the doctor is hoping for a near-complete recovery.


“Clinically, he has improved dramatically,” he said.


Middle East News Headlines – Yahoo! News





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New Online Privacy Loophole Lets Facebook Advertise to Kids






Mark Zuckerberg‘s been eager to find a way to get more kids on Facebook for years, and on Wednesday, the Federal Trade Commission handed it to him on a platter. That might be overstating it a little bit. It’s more like the FTC served it to him on a platter covered in plastic wrap with a note attached that says “Do not open.” Nevertheless, should Facebook decided to see what’s inside, experts in online privacy for children say the social network could legally start peddling everything from kids’ bicycles to that new gender-neutral Easy Bake Oven.


RELATED: German Official Urges Citizens to Stop Using Facebook






After months of deliberating and plenty of lobbying on both sides of the issue, the FTC updated the controversial Children’s Online Privacy Protection Act (COPPA) this week. The changes were absolutely designed to better protect children in the privacy-invading era of social media, especially from the data-hungry advertisers who want to sell them things. Websites like Facebook don’t allow kids to sign up without their parents permission, generally because COPPA has prohibited them from collecting the kinds of information they need to serve them ads. And why would they want a user to whom they couldn’t serve ads? Under the new FTC rules, parental permission is required for just about anything a kid would do on Facebook, including uploading photos, videos and geolocational information. Tracking tools like cookies are also verboten without a parent’s permission.


RELATED: What Police Learn About You When They Subpoena Your Facebook Account


But there’s a loophole. The new rules say very plainly that no parental permission is needed “for the sole purpose of supporting the website or online service’s internal operations, such as contextual advertising, frequency capping, legal compliance, site analysis, and network communications.” The key phrase there is “contextual advertising,” which is an ad product Facebook has been working on for a while. Facebook’s version basically reads your News Feed and shows you ads that are relevant, or contextual, to what you’re reading. As a few people have pointed out, this opens a door for Facebook to start exploring the idea of ad-supported profiles for kids. Alan Simpson, the vice president of child privacy advocacy group Common Sense, isn’t happy about this idea. “Common Sense doesn’t like this part, and the industry lobbyists probably do,” he told TechCrunch Monday evening.


RELATED: What Facebook Does to Kids’ Brains


Now, there are a lot of ifs in this scenario. Based on the magnitude and sensitivity of the issue, Facebook probably doesn’t want to go scaring a bunch of parents by sneaking through loopholes to show their kids Easy Bake Oven ads. It has been nearly a decade and a half since COPPA got an update, though, and Mark Zuckerberg isn’t really known for his patience. Of course, Facebook could do what they’ve been doing for ages, which is look over their shoulder while kids lie about having permission and sign up anyways.


Social Media News Headlines – Yahoo! News





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HIV cases decline for black women, increase for gay men: CDC






ATLANTA (Reuters) – Fewer black women in the United States are being infected with HIV, but the number of young gay and bisexual men infected is rising, the Centers for Disease Control and Prevention said on Wednesday.


Between 2008 and 2010, the number of newly infected black women dropped 21 percent, according to the CDC report. Yet despite the decline, they still accounted for 70 percent of all new HIV cases among women, the federal health agency said.






The rate of new infections for black women was 20 times higher than the rate for white women, the CDC said.


The number of new infections among young gay and bisexual men increased by 22 percent during that same two-year period, the CDC said.


The number of new HIV infections diagnosed annually in the overall U.S. population remained unchanged between 2008 and 2010 at about 47,500, according to health officials.


Public information campaigns on HIV prevention and testing seem to be working in lowering the number of new infections among African-American women, said Joseph Prejean, chief of the Behavioral and Clinical Surveillance Branch in the CDC’s division of HIV/AIDS Prevention in Atlanta.


“We are encouraged to see some declines among African-American women,” Prejean told Reuters. “They’ve been one of the most severely affected populations. We’re cautiously optimistic that this could be part of a longer-term trend.”


Among young gay and bisexual men, efforts to fight HIV have not been as effective, possibly because of advances in treatment for AIDS, the immune disorder caused by HIV, Prejean said.


“We do realize that many men who have sex with men do probably underestimate their personal risk and believe that treatment advances minimize the health threat,” Prejean said.


Even though treatment can prolong the life of an AIDS patient, Prejean cautioned that “their life really does change. They then begin to take medication and will take medication for the rest of their lives,” he said.


HIV is an incurable infection that costs $ 400,000 to treat over a lifetime, CDC Director Dr. Thomas Frieden said last month after another government report showed more than half of young Americans infected with HIV were not aware they had it.


Young people ages 13 to 24 account for 26 percent of all new HIV infections in the United States, the earlier CDC report said.


The report released on Wednesday said nearly two-thirds of new HIV infections in 2010 resulted from men having sex with other men. Young black men who have sex with men account for more new infections than any other subgroup, government health officials said.


“Because gay men account for 66 percent of all new infections, we must increase the focus of our prevention programs for gay men, particularly young and black gay men,” said Michael Ruppal, executive director of The AIDS Institute.


(Editing by Colleen Jenkins and Dan Grebler)


Sexual Health News Headlines – Yahoo! News





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